The Definitive Guide to ceesdekker
The Definitive Guide to ceesdekker
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‘Yes, which is about ideal. I seek out a physical knowledge of Organic units inside a bottom-up way. I believe you could possibly distinguish three traces of analysis in my group for the time being. The 1st concerns chromosome construction: How does one obtain a metre-very long DNA polymer folded and organised in such a microscopic cell? We have now created visualisation tactics that make it possible for us to study how, as an example, SMC proteins loop DNA (movie on Youtube) so that you can Develop up chromosomes.
Our team reports bacterial cell division and is aiming to represent a ‘bottom up biology’ in synthetic cells which can autonomously divide. Our key curiosity lies in cell division, chromatin structure, and spatial Command.
[Laughs] ‘It absolutely was unquestionably an awesome hazard! At some time, I had been properly mindful that it could go Mistaken and that I could turn out to be much less thriving, but I just disregarded that. Curiosity has generally been my strongest driving pressure. And fortuitously it all labored out.’
Considering the fact that 2000, Dekker has shifted the key concentration of his work in direction of biophysics where by he research the Homes of one biomolecules and cells utilizing the tools of nanotechnology. This modification of field was driven by his fascination to the extraordinary functioning of biological molecular constructions, and also via the very long-time period perspective that a lot of exciting discoveries is often envisioned in this area.[5] Recent traces of investigate in his biophysics team are in the areas of:[6]
2012, discovery that nucleoid occlusion underlies the accuracy of bacterial mobile division; and very first ever review in the dynamics DNA supercoils and the invention of supercoil hopping
Electrical transportation in monolayers of phthalocyanine molecular wires and AFM imaging of a single wire bridging two electrodes
Many associated developments followed, exactly where our group set up distinct transistor variants including single-electron transistors at space temperature and intramolecular nanotube junctions that acted as rectifying diodes, and coupled several transistors into smaller evidence-of-theory electronic circuits.
He also identified time to jot down numerous guides, deliver Pretty much forty thousand tweets and lead An effective research group at Delft College of Technologies. ‘It doesn’t sense like function’, he claims. ‘I’m just terribly curious.’
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‘The fantastically delicate way during which components in nature functionality hardly ever ceases to amaze me. If we clear up the puzzle of how daily life came into being, I expect that my amazement for the complexity of development can have elevated and with it my awe for the greatness with the Creator.’
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Cees Dekker is Distinguished College Professor at TU Delft. Experienced for a physicist, he pioneered nanotechnology with quite a few discoveries on carbon nanotubes during the nineteen nineties. Considering the fact that 2000, he moved to one-molecule biophysics and nanobiology. His present-day investigate concentrates on (i) nanopores for protein sequencing; (ii) chromosome framework, particularly SMC motor protein; and (iii) creating a living artificial mobile from lifeless molecules. Dekker is really an elected member on the KNAW and fellow on the APS plus the IOP.
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Dekker heeft fundamentele ontdekkingen gedaan op het gebied van koolstof nanobuisjes. Mede vanwege deze werkzaamheden is hij al jaren de meest geciteerde fysicus in Nederland. Tegenwoordig onderzoekt hij satisfied enkel-molecuultechnieken de biofysica van moleculen in de biologische cel. Dekker is naast zijn wetenschappelijk werk ook bekend vanwege zijn belangstelling voor de relatie tussen geloof en wetenschap en de discussie rond clever design in 2005. (nl)